Most applications have the ability to redefine keyboard shortcuts. Meaning, if there's a certain feature that you use often, but there's no keyboard shortcut for it, you can very easily choose Edit > Keyboard Shortcuts (in AI, PS and ID for example), and assign one for that feature. In fact, if you scroll towards the bottom of the list of Menu Commands, you'll find that you can even assign keyboard shortcuts to some items that don't appear in menus at all.
And since it might be bad to mess up your keyboard shortcuts, you have the ability to save your own customized sets of keyboard shortcuts. In fact, InDesign ships with a keyboard shortcut set for QuarkXPress users. If you've just made the switch to InDesign and you are still used to all of the Quark shortcuts, you can switch to the keyboard shortcut set for Quark. This way, all of your familiar Quark shortcuts work in InDesign.
My personal opinion is that if you also use other Adobe apps, using a Quark set of shortcuts in InDesign isn't that much of a help in the long term. However, I do see value in the short term, when users first make the switch, to use familiar shortcuts as a "crutch" to prevent frustration and to help build familiarity in the new application. When I made the switch from Quark to InDesign, I used the Quark shortcuts for several days before I abandoned them for the (mostly) consistent set of shortcuts across all Adobe applications.
But I always did wonder why Adobe never supplied a FreeHand set of shortcuts for Illustrator. I made the switch from FreeHand to Illustrator way before Illustrator had the ability to assign custom keyboard shortcuts. But I know that at the time that I made the move, it would have helped to have that crutch to lean on.
So with that in mind, I've gone ahead and created a FreeHand MX set of shortcuts that you can load into Illustrator CS2. If you're a FreeHand user who recently made the transition to Illustrator (or if you're currently evaluating Illustrator CS2), feel free to download this file.
Once you've downloaded and unzipped the file, drop the file into the following folder on your computer (the file is cross-platform):
C:\Documents and Settings\username\Application Data\Adobe\Adobe Illustrator CS2 Settings
Mac OS X:
username > Library > Preferences > Adobe Illustrator CS2 Settings
Then relaunch Illustrator, choose Edit > Keyboard Shortcuts and choose FreeHand MX from the Set pop-up menu.